Best Hollywood Duos Fans Adore in Films: Dwayne Johnson-Kevin Hart to Matt Damon-Ben Affleck

Some pairings in Tinseltown have an undeniable onscreen presence that is hard to resist. Here're 7 most iconic Hollywood duos that have created magic with their memorable performances.

Published on May 31, 2025  |  03:40 PM IST |  135K
Dwayne Johnson, Kevin Hart, Matt Damon and Ben Affleck (Getty Images)
Dwayne Johnson, Kevin Hart, Matt Damon and Ben Affleck (Getty Images)

To make a memorable film, a director needs a good script and a suitable cast. And some actors are just so comfortable working together that their offscreen camaraderie translates perfectly to onscreen magic. Some pairings are just made in heaven, be it because of their perfectly timed comedic routine or polar opposite personalities. Their interactions, banter, and sometimes even fights grab fans' attention. Reminding us that every hero needs a sidekick and every great story needs a duo that balances, complements, and elevates each other.  

Advertisement

Two is better than one, and these iconic duos have shown us that they can make audiences return to the theatres to watch them again and again. With their back-to-back hits, they have proven that when the right actors come together, the result is pure cinematic gold. 

Check out the 7 best Hollywood duos of all time.

Ben Affleck and Matt Damon

Ben Affleck and Matt Damon

First Movie Together: Field of Dreams (1989)

Iconic Movies They Starred In: Good Will Hunting (1997), Chasing Amy (1997), Dogma (1999), Jay and Silent Bob Strike Back (2001), The Last Duel (2021), Air (2023), and The Instigators (2024)

On-Screen Chemistry: These two childhood friends have portrayed both comedic and dramatic roles in films together. Their genuine connection translates to the screen, and fans love to see the two share screen space. Their breakout moment came with Good Will Hunting, which they co-wrote. The two won an Oscar for Best Original Screenplay for the 1997 film. 

Why They’re Iconic: Whether it's writing a gripping screenplay or showcasing their camaraderie on screen, the two always bring the best out of each other. They have frequently collaborated throughout their careers and have even co-founded production companies to ensure they have creative control over their projects. Their polar opposite personalities make them the best fit for any script.

Advertisement

Dwayne Johnson and Kevin Hart

Dwayne Johnson and Kevin Hart

First Movie Together: Central Intelligence (2016)

Iconic Movies They Starred In: Jumanji: Welcome to the Jungle (2017), Fast & Furious Presents: Hobbs & Shaw (2019), Jumanji: The Next Level (2019), and DC League of Super-Pets (2022)

On-Screen Chemistry: The unlikely pair has given us some of the most memorable films in the last decade. Their offscreen friendship has led to several successful onscreen partnerships and box office hits. They love to roast each other on the screen, and fans are all in for their banter. 

Why They’re Iconic: Johnson and Hart are one of Hollywood's most beloved comedic duos in recent times. Johnson's physical comedy blends well with Hart's quick wit and funny antics. Their infectious energy can make any film a hit. Their connection is also seen on social media posts and interviews, making them a standout Hollywood pair. 

James Franco and Seth Rogen

James Franco and Seth Rogen

First Movie Together: Pineapple Express (2008)

Advertisement

Iconic Movies They Starred In: The Green Hornet (2011), This Is the End (2013), The Interview (2014), The Sound and the Fury (2014, Rogen is cameo only), The Night Before (2015), Sausage Party (2016), The Disaster Artist (2017), and Zeroville (2019)

On-Screen Chemistry: The pair has starred in nine films together. Their first outing together was in the 1999 TV series Freaks and Geeks, and as the title suggests, one makes for a great freak and another a great geek. Over the years, they have become famous for their stoner comedies and outlandish films. 

Why They’re Iconic: Just like Hart and Johnson, Rogen and Franco are considered one of the most iconic comedic duos in Hollywood. Together, they have acted in several cult-favourite films. Their onscreen connection has always resonated with the audience.

Tina Fey and Amy Poehler

Tina Fey and Amy Poehler 

First Movie Together: Martin & Orloff (2002)

Iconic Movies They Starred In: Mean Girls (2004, Man of the Year (2006, cameos only), Baby Mama (2008), Anchorman 2: The Legend Continues (2013, cameos), Sisters (2015), and Wine Country (2019)

Advertisement

On-Screen Chemistry: Fey and Poehler's friendship goes back almost three decades. They created history when they became the first female co-anchors of Weekend Update on Saturday Night Live in 2004. They were later hired to cohost several award shows because of their amazing chemistry and comedic timing.

Why They’re Iconic: Fey and Poehler have opened doors for countless women in comedy. Their punchlines and smart humor have struck the perfect blend of funny and fearless. The way they play off each other makes them fan favorites. Together, they have created iconic characters and moments that continue to shape pop culture. 

Ben Stiller and Owen Wilson

Ben Stiller and Owen Wilson 

First Movie Together: The Cable Guy (1996)

Iconic Movies They Starred In: Permanent Midnight (1998), Meet the Parents (2000), Zoolander (2001), The Royal Tenenbaums (2001), Meet the Fockers (2004), Starsky and Hutch (2004), Night at the Museum (2006), Night at the Museum: Battle of the Smithsonian, Little Fockers (2010), Night at the Museum: Secret of the Tomb (2014), and Zoolander 2 (2016)

On-Screen Chemistry: Stiller and Wilson have an amazing comedic chemistry. Their effortless rapport and personalities make them a dynamic duo in Tinseltown. Together, they have acted in 12 films between 1996 to 2016. They are experts at blending absurd humor with genuine moments of connection.

Why They’re Iconic: Whether as frenemies or unlikely partners, they bring out the best in each other. They deliver laughs with every scene, and audiences love to see them together. 

Advertisement

Robert De Niro And Al Pacino

Robert De Niro And Al Pacino

First Movie Together: Raging Bull (1980)

Iconic Movies They Starred In: Once Upon a Time in America (1984), Goodfellas (1990), A Bronx Tale (1993), Casino (1995), The Good Shepherd (2006), and The Irishman (2019)

On-Screen Chemistry: De Niro and Pesci have shared screen space in over seven films in their decades-long collaboration. The two always elevate each other’s performances, leaving the audience glued to the screen. Their synergy has left an indelible mark on cinema, and fans love to see them together in different roles.

Why They’re Iconic: The two have delivered some of the most powerful performances in film history. While De Niro has a brooding and restrained presence on the screen, Pesci exudes a fiery presence and sharp energy.

Samuel L. Jackson and Bruce Willis

Samuel L. Jackson and Bruce Willis

First Movie Together: Loaded Weapon 1 (1993)

Iconic Movies They Starred In: Pulp Fiction (1994), Die Hard with a Vengeance (1995), Unbreakable (2000), and Glass (2019)

On-Screen Chemistry: Willis played a cameo role in Jackson’s action spoof film Loaded Weapon 1. Fans loved them together, and within two years, they collaborated again on a Die Hard Sequel. They have also acted in three cult films. They're one of the best action-thriller duos in Hollywood. While Jackson rules the screen with his intellectual gravitas, Willis brings his rugged and cool vibes to the fore.

Advertisement

Why They’re Iconic: Willis and Jackson are nothing alike, and they bring different traits to the films they work on. The push-and-pull between their styles elevates every scene they share.

If you are planning a movie night with your best friend and you are looking for films that have Hollywood's best duos, add these films to your binge list and enjoy your weekend. Whether you are looking for laughs or action-packed sequences, these films will entertain you. 

ALSO READ: Cannes 2025: Aubrey Plaza Makes First Red Carpet Appearance Since Husband Jeff Baena’s Tragic Death With Co-Star Margaret Qualley

FAQs

Who is the most famous Hollywood duo of all time?
Ben Stiller and Owen Wilson 

What makes a Hollywood duo successful?
Actors who share natural on-screen chemistry make for an amazing Hollywood duo

Which movie duos have made the most box office revenue?
Samuel L. Jackson and Bruce Willis

Which actors have had the best on-screen chemistry in Hollywood in the last decade?
Dwayne Johnson and Kevin Hart

About The Author

Kirtika Katira might be an entertainment journalist by profession, but she is a storyteller at heart...

Advertisement
Advertisement

Latest Articles